Saturday, March 14, 2020
European Government in the 19th century1 essays During the twentieth century, Europe went through many changes in politics and trends. On June 28, 1914, Serbian revolutionaries assassinated Archduke Francis Ferdinand, the heir to the Austrian and Hungarian thrones, and his wife, Sophie. With Germany behind Austria-Hungary, Austria attacked Serbia on July 28th. The following day, Russia ordered full mobilization and in effect declared full all out war. Germanys plan was to knock out France by going through neutral Belgium and then taking out Russia. On August 2, 1914, Germanys plan to pass through neutral Belgium failed when Belgium refused to let German forces through. Germany intern attacked Belgium. On August 3rd,Great Britain joined forces with France, which started the First World War. A major social impact in Europe occurred during World War I. With almost all able-bodied men fighting in the trenches, this caused a great demand for workers. Jobs were available for everyone. This also brought about change for labor unions. The roll of women changed for the better during this time. Women basically took over the labor forces in Russia. In Great Britain, women were driving streetcars and buses. Women became more prominent in society. Showing up as mail carriers, bank tellers, and even police officers. In 1917, Russia went through two revolutions that cause Russia to with draw from the war. In March of 1917, the Duma declared a provisional government. A month later, Lenin returns from exile to denounce the provisional government. All social classes were in favor of this drastic move. It would create better wages for workers and more food. In 1920, Lenins Red army retook Belorussia and the Ukraine. In the spring of 1918, Germany launched its last attack on France. With the United States backing Britain and France, the triple entente finally crushed German forces. In January of 1919, in Versailles, The Treaty of Versailles was signed...
Wednesday, February 26, 2020
Congestion Problem in Beijing, China - Research Paper Example This is the political center of China, and it is among the modern and dynamic cities in cities. In just over a decade, the population Beijing has grown by nearly 42 per cent to nearly 20 million people, and this makes it one of the fastest growing cities in the world (Feng, 2012). Unlike the previous years, the scene of bicycles as previously witnessed has been replaced with by parked cars and crowded subways. The number of registered automobiles grew from 1.9 million in 2002 to more than 5 million automobiles in 2012 (Feng, 2012). It is important to remember that Beijing has more than 15 subways and rail lines totaling to more than 450 kilometers, one of the longest in the world. Despite this, congestion is still a major problem. The question therefore remains, what causes this congestion? The congestion in this city is caused by a number of factors. First, there is the phenomenon of motor and non-motor vehicle mixed traffic (MNM) (Hua, et al, 2013). This is the case where traffic is characterized by both motor vehicles and other non-motor vehicles. In Beijing, there are a high number of bicycles, and this poses a major challenge to traffic management. It is difficult to control the bypassing of vehicles, pedestrians and cycles. This confusion disrupts the flow of traffic, leading to congestion.
Monday, February 10, 2020
News & Views - Essay Example What is never mentioned, however, is that everybody has the right to read and get the most basic information about any disease including breast cancer. This news brief seeks to inform everyone that breast cancer is real, and with ever increasing research, the root cause hence the cure for the diases shall be known. Since it was rerpoted that breast cancer exists, a number of studies have sought to understand the its real cure. In most recent studies, it has been indicated that KLf8 to MMP14 signaling is the principle facilitator of metastasis of breast cancer (Lu et al, 2013). According to Lu et al KLf8 to MMP14 signaling helps in progression of breast cancer in human. Lu et al hinted that KLF8 also called the Kruppel-like factor 8, plays a significant role in regulating critical transcription gene, which is a gen responsible for causing cancer. However, what remains unclear is the conditions and mechanism of the operation of this gene. According to Lu et al, KLF8 facilitates the act ivity, rather than the matrix metalloproteinase expression. Background. The debate on the cause and treatment of breast cancer has never ceased. There is lacking scientific proof that breast care can be cured. The number of studies that have sought to ascertain the real cause of this deadly disease has always increased (Ara, & Deyama, 2000; Cristofanilli, 2006). However, most were focused on the initial stages of breast cancer. According to Nawrocki-Raby and Gilles (2003) metastatic cell can help increase the survival chances of a breast cancer patient. Symowicz and Adley (2007) noted that Kruppel-like factor 8 an important cancer promoting protein occurs in different categories of cancers. Zhao and Reiske (1998) KLF8 is one factor that targets the promoters of different oncogenes or the genes that suppress tumor for the transcriptional repression or activation. The function of KLF8 in breast cancer was identified, when KLFB was identified as a kinase focal adhesion downstream effec tor.KLF8is known to be overexpressed in the human cancers that are invasive, such as breast cancer, hence promoting the invasion of the breast cancer cells togehte rwith metastasis. This happens through the propulsion through cycle cell progression. Due to the valid functions of KLF8, the protein is always regulated at the post transitional and transitional levels together with the localization of the nuclear. From the conducted studies, there is no documented study that reports on the molecular mechanism signalling by KLF8 and known to facilitate breast cancer. IN metastasis, and tumor invasion the matrix metalloproteinase has a vital function to play. They operate downstream of FAK by enhancing tumor metastatis. Another study on this field identified MMP9 as one direct transcriptional target of activation by KLF8 together with the mediator promoting KLF8 breast cancer invasion of cell. Togehter with that finding, the study established that KLF8 can regulate the MMP2 3nzyme functio ns with no effect to the expressional levels. Explanation. For the invasiveness of breast cancer ceel, the KLF8 upregulation of MMP14 is vital. A study by Lu et al (2013) showed that the KLF8 overexpression in the cells of MCF-10 would facilitate the knockdown and invasion of the KLF8 inside the MDA-MB-231 invasion cells. This study found that MMP9 is a transcriptional target of activation of the KLF8 in the cells which take part in the invasion of KLF8 invasion dependent (Symowicz & Adley, 2007). The activity of MMP2 is reported to be upregulated
Thursday, January 30, 2020
High School Girls Essay 1. In my High School, the experience was somewhat different. In the article it says that the boys stared at the girls passing and rated the different parts of their body from one to ten. In my high school days, the boys striped us with their eyes and we felt that they can see inside our clothes. They also made lewd comments. 2. We felt harassed and humiliated and degraded as Rachel and her friends felt. It used to make me very angry but my friends never let me retort as these boys were Ã¢â¬Ëbad boysÃ¢â¬â¢. We were frightened of them. 3. We were taught in home as well in school to keep away from these kinds of boys. As a result the girls rarely talked about the issue. Even if we spoke about it, we never thought of taking actions against the boys who harassed us. 4. Individually sometimes one girl would retort for misbehaving with her. One of the girls in our class once turned back and told the boy who was teasing her to stop it or else she will the principal. 5. Rachel and the other girls taught those boys a lesson. The girls in my school never thought of taking action against the boys. It was very difficult to convince the girls to take action in a group. The common advice was to ignore them. 6. The boys who teased us were the lot who did not study in school. They had all kind of bad habits like smoking, taking alcohol and drugs and they were of rich families. They were notorious. The girls in my school were too scared of these boys to take any sort of action against them. 7. The teachers in my school did not approve of this kind of behavior. There were some strict teachers in our school, those boys stood clear of their path. If any teacher saw them behaving in this manner, they would complain to the principal, who would punish them heavily. 8. The other boys in the school did not confront them as this would lead to fighting and abusing. They did not tell their peers as they did not want to get involved. 9. I think that school teachers and administrators can stop this kind of thing from happening in school in two ways. First, they can make the girls aware of eve-teasing and the result of keeping silent. They should be made aware of the fact that keeping silent is not the solution. It only increases and do not end it. Second, the school authorities should warn those boys that they will be heavily punished and even rusticated if they continue such behavior. Summary: In the article, the boys of high school during lunch time harass the girls but staring and rating different parts of their boy from one to ten. One girl among them, whose name was Rachel also faces similar situation in spite of friendly with them. She feels very humiliate and degraded by the action. She along with other girls plans and teaches them a lesson. They sit in the same bench, rate them and grab them as they used to do. After the episode, those boys stop harassing them.
Wednesday, January 22, 2020
The Importance of EDI To stay competitive in today's global economy, businesses are being forced to re-evaluate the way they do business with their customers and their vendors. We cannot afford to close our eyes to advances in technology in the way many businesses have done in the past and continue to do even now. It is a question of do it or die in the competitive world of products and services where the well informed and the technologically equipped will reap the rewards of success. Our company is already behind others in technology and efficiency by not having EDI. Without EDI, our internal processes have poor response times, excessive paperwork floating around and potential errors that should not be necessary as well as wasting personnel time doing a work that could be automated. When business begins to trade or share core information, the return of technological investment is clear and then we realize the true value of EDI. We should not stay behind our competitors and should start now a process of implementing EDI in our company, improving our efficiency and productivity, and reach higher levels of customer satisfaction. When EDI is used as a tool to enable process change and help achieve business goals, significant benefits can be reached. EDI enhances all parts of the business process, and we would expect some impacts, such as: Ã · Reduced Process-Time: the need to send and receive information is crucial in todayÃ¢â¬â¢s business world. With EDI, data can be sent and received in seconds and 24 hours a day and 7 days a week, thus allowing business to continue outside the normal business day, and the turnaround time for a business transaction can be reduced from days to hours and, in some instances, to minutes or even seconds. Ã · Increased Efficiency: the major part of data entry tasks is generated from a computer. When companies develop compatible electronic documents, data is never copied, re-keyed, or manually filed, freeing employees for more important activities, eliminating tedious work and reducing the risk of human error. Ã · Optimized Inventory: managing inventory is a critical issue for any business. EDI can provide faster and more accurate information about production, buying and delivery needs. It is a link between customer, seller and vendor thus leading to improved inventory management and reduction in inventory levels. For initial EDI projects, limited objectives with perceivable benefits should be our first step.
Tuesday, January 14, 2020
When someone hears the term Ã¢â¬Å"higher educationÃ¢â¬ the first thought tends to be college, of course. College has always been thought of as the one-way ticket to a high salary occupation. The reality of the situation is that while that may be true in some cases, itÃ¢â¬â¢s not as easy at it seems to receive that ticket aka the BachelorÃ¢â¬â¢s degree. College tuition is a large amount and itÃ¢â¬â¢s even more expensive to attend college only to drop out. This leaves the student with no degree and vast amounts of debt. That debt is averaging 20,000 dollars for four years of schooling. Higher education is beneficial for anyone with the dedication to attending and knowing what they are striving for with while doing so. Achieving a BachelorÃ¢â¬â¢s degree or a B. A. is a worthwhile goal for just about everyone. Why is it worth the time, effort and money to receive this diploma? Charles Murray in his article Ã¢â¬Å"Are Too Many People Going to College? Ã¢â¬ states, Ã¢â¬Å" Employers value the B. A. because itÃ¢â¬â¢s a no cost (for them) screening device for academic ability and perseveranceÃ¢â¬ (pg. 233). The train of thought for employers is that the students with the drive and capabilities to succeed are the oneÃ¢â¬â¢s that will attend college. This makes it close to impossible for a person with only a high school diploma to even be considered for a variety of jobs. Brian Kelly in his article Ã¢â¬Å"Is College Still Worth It? Ã¢â¬ has come across the same findings as Murray. He reports, Ã¢â¬Å" Hiring managers will tell you that creative intelligence and an ability to communicate are more useful in the long term. As a proven work ethic which is why persisting through four years of college is an admirable credential in itselfÃ¢â¬ (pg. 8). College is supposed to teach a person how to think and work hard. That is something that any employer values greatly. The greater chance of a fulfilling career isnÃ¢â¬â¢t the only benefit to receiving a B. A. In 2007 the Census Bureau reported that the average college graduate had a yearly income of $57, 181 (Wilson pg. 260). The average high school graduate pulled in around $31, 286 yearly, leaving the college graduates earning around 80% more annually (pg. 260). Wilson also states that according to the Census Bureau the college graduate will earn around one million dollars more than the high school graduate (pg. 260). This is reason enough for many people to buckle down for the time it takes to earn his or hers degree. A fear for many is that the debt someone will leave college with will be unmanageable. The reasoning for this being unemployment rates as well as the fear of how long it will take to pay off his or hers debt. ItÃ¢â¬â¢s true unemployment is a crisis that many are facing but itÃ¢â¬â¢s much scarier to be only a high school graduate in the economy currently. The rates of unemployment for a BachelorÃ¢â¬â¢s degree holder over twenty-five is estimated to be around 4. 4% (Wilson pg. 260). For a high school diploma holder over twenty-five the unemployment rate is an even greater number at 9. 3% according to the Bureau of Labor Statistics (pg. 260). As for paying off the debt accumulated in college, those figures arenÃ¢â¬â¢t as frightening. According to Sandy Baum, a senior analyst at College Board, Ã¢â¬Å"A student with twenty thousand dollars of debt should be able to make at least that amount in extra earnings in one to two yearÃ¢â¬â¢s time simply by having earned a college diplomaÃ¢â¬ (qtd. in Wilson). What is the key to unlocking the door for a brighter future? Apparently itÃ¢â¬â¢s a B. A. but if this is the case then why are dropout rates so high? When students are making the decisions to go to college, they are typically pushed to attend college rather than doing so out of free will. These students are the oneÃ¢â¬â¢s that parents, teachers, and guidance counselors assume will succeed the most in that kind of environment. The truth is rather sad when it comes to how the students actually fared in their academic pursuit. Dana Goldstein in her article Ã¢â¬Å"Should All Kids Go to College? Ã¢â¬ informs that only fifty three percent of students actually finish their degree in four years, and half the students that attend a two-year college drop out before finishing. But this isnÃ¢â¬â¢t the only surprising information she writes about in her article. There is another group of students who unlike their peers, arenÃ¢â¬â¢t pushed as much into attending college. Kati Haycock, president of Think Tank Trust in Washington, DC, shocks with her statement of, Most schools sill resist the idea that all kids can and should be college-ready. By continuing long-standing practices of sorting and selecting, they created what is essentially an educational caste system- directing countless young people, especially low-income students and students of color, away from college-prep courses and from seeing themselves as Ã¢â¬Ëcollege materialÃ¢â¬â¢ (qtd. n Goldstein). With these standards given in high schools these students pushed away from college will not ever think of themselves as able to perform well in a college environment, which greatly limits their future professionally. Goldstein shows in her article the research showing that with the decline of the manufacturing economy these students are the ones who would gain the most from the four-year college experience. The question is now, why are these students unable to realize their potential or stay focused in college? Most of the time these teenagers are unable to say what they want to do with their careers or lives. Going to college isnÃ¢â¬â¢t easy for anyone without a clear idea of what their striving for, which makes the entire experience even more frustrating for them. So how can these students go into college somewhat knowing what they want to do with their time there? The best solution is to allow these teenagers to explore the professional world while still in high school. If they can do that, then they wonÃ¢â¬â¢t spend extra time or money changing their majors all throughout college unable to decide what their desires are. There is a program that has been implemented in a few schools across the nation called Career and Technical Education or CTE (Goldstein). These programs integrate school with real world occupational training so that students can have hands on experience with a job that they would like to pursue in college. The training available to these students includes internships, dual enrollment and hands on work out in the field (Goldstein). All of this is done while in high school accomplishing their high school diploma and getting a head start on college. Programs like the previous are great ideas that the government has been using to help these students struggling find their goals. It may be a while until these CTE schools are seen more but at least the students able to take advantage of them are showing the country how beneficial the programs are. With ideas like this, it is possible to cut down on the money and time wasted during college for someone who isnÃ¢â¬â¢t positive they would like to be there. It also allows the students who are judged due to unfair standards to prove that they are college material and able to do great things. There would be less wondering about whether or not they want to attend college because they have experience with the career of their choosing and are able to map out their future much more clearly. Overall the idea is yes, higher education is worth the price. The BachelorÃ¢â¬â¢s degree alone can take someone to higher levels than just a high school diploma. College is costly, it is time consuming, and it is hard but when someone is dedicated it becomes increasingly easier. The solutions to making college more achievable for everyone isnÃ¢â¬â¢t ever going to be easy but there are steps that can be taken in the right direction. As long as students arenÃ¢â¬â¢t discriminated against or pushed into something they are unsure of, when the time is right for them to attend college they will do so in a way that will benefit them the most. Add in programs like the Career and Technical Education schooling and these students can come out on top ready for the work force. Higher education may not be for everyone, but for the people who do take the challenge reap benefits for the rest of his or hers lives.
Monday, January 6, 2020
There is a very controversial ethical dilemma in the realm of medicine. It is the ethical rock bottom to some, while for others it marks an escape from their doomed state. This controversial topic is called Ã¢â¬Å"Physician-Assisted DeathÃ¢â¬ , also sometimes referred to as Ã¢â¬Å"Assisted SuicideÃ¢â¬ . This issue is often an emotionally charged one, as many patients who request this type of service are terminally ill and wish to die peacefully, without pain, and with their dignity intact. Assisted death is not however legal for anyone who is not terminal, Ã¢â¬Å"if someone has a chronic illness that is not terminal, that individual is not eligible for assisted suicide under any proposal in the U.S., nor under the Oregon Death with Dignity Act.Ã¢â¬ (Golden, 2014) Many requests for assisted suicide are usually for one of the following reasons: Ã¢â¬Å"Being afraid of what the future may hold, experiencing burnout from unrelenting disease, having the wish and need for control, ex periencing depression, or experiencing extremes of suffering, including refractory pain and other symptoms.Ã¢â¬ (Pereira, 2011) Our current patient is Mr. William Blake. Mr. Blake is 68 years old, married for 40 years. Father and Grandfather too many children. He is a retired school teacher and Sunday school teacher. Mr. Blake has terminal lung cancer, and does not wish to die at the end of a long and drawn out battle with his disease. Mr. Blake has been healthy most of his life, except for his habit of smoking which has caused himShow MoreRelatedThe Ethical Dilemma of Assisted Suicide for Nurses878 Words Ã |Ã 4 Pagesin a way that is abiding with the ethical responsibilities of the nursing profession and quality in nursing care. The Code of Ethics has excellent guidelines for how nurses should behave, however; these parameters are not specific. They do not identify what is right and wrong, leaving nurses having to ultimately make that decision. Ethics in nursing involves in dividual interpretation based on personal morals and values. Nursing professionals have the ethical accountability to be altruistic, meaningRead MoreNurse Jackie And Assisted Suicide1364 Words Ã |Ã 6 PagesJackie and Assisted Suicide Ethical dilemmas exist everywhere around us in everyday situations. 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Since Oregon and other states implemented the legalization of physician assisted suicide, the debates continues. The U.S. Supreme Court decisions in 1997 and the Pain Relief Promotion Act of 2000 (H.R. 5544) have kept these topics on the policy of the national agenda, along withRead MoreThe Legal Ethics Of Assisted Suicide1130 Words Ã |Ã 5 Pagessignificant reexamination and for the most part, experience continued support of the legal system. Ethical/Legal Model The issue of assisted suicide places the advanced practice nurse in a precarious ethical and legal position. While the goal of the nurse is to provide care for the patient and to provide appropriate and safe responses to patient requests, assisted suicide is quite the dilemma in regards to a request to perform acts considered illegal with criminal implications and forfeiture of licensureRead MoreThe Ethical Dilemma Of Euthanasia Essay1515 Words Ã |Ã 7 Pagesthat suffering is so great, the only release from that suffering is death. That is not murder. That is no suicide. That is mercyÃ¢â¬ (McDonald, 2015) This quote from Lecretia Seales husband helps to put many peoples situations into context when it comes to the debate of euthanasia or assisted suicide. The ethical dilemma in this case is that of Lecretia Seales request to die of assisted suicide in 2015. This deals with a current issue not only as SealesÃ¢â¬â¢ appeal to the New Zealand high courts for law